产品货号：
Z12334
中文名称：
CD11a/Integrin Alpha L/ITGAL抗体
英文名称：
Anti-CD11a/Integrin Alpha L/ITGAL Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD11a/Integrin Alpha L/ITGAL Antibody |
| 指标别名 | CD11A;Integrin alpha L;ITGAL;LFA 1;LFA 1A;LFA1A |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC-F,ICC,FCM |
| 基因名称 | ITGAL |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CD11a recombinant protein (Position:F161-L349).Human CD11a shares 73.7% mino acid (aa) sequence identity with mouse CD11a. |
| 实际分子量 | 129KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CD11a,also known as ITGAL or LFA-1,is a human gene which functions in the immune system.It is mapped to 16p11.2.CD11a is involved in cellular adhesion and costimulatory signaling.It is the target of the drug efalizumab.CD11a encodes the integrin alpha L chain.Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1),which is expressed on all leukocytes.CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands,ICAMs 1-3 (intercellular adhesion molecules 1 through 3),and also functions in lymphocyte costimulatory signaling.It is one of the two components,along with CD18,which form lymphocyte function-associated antigen-1. |
| Uniprot ID | P20701 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry in fixed cells(ICC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
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